European Immunology

Immunogenetics

Immunogenetics investigates the genetic basis of immune responses, focusing on genes that encode molecules involved in immune recognition, activation, and regulation. Key areas include human leukocyte antigen (HLA) genes, which determine compatibility in organ transplantation and influence susceptibility to autoimmune diseases and infectious diseases. Immunogenetic studies also explore polymorphisms and gene variations associated with immune response variability among individuals, including responses to vaccines and immunotherapies. Understanding immunogenetics helps personalize medicine by predicting disease risks, optimizing treatment strategies, and developing targeted therapies based on individual genetic profiles.