European Immunology

Cancer Immunology and Immunotherapy

Cancer immunology explores how tumours evade immune surveillance and manipulate the immune microenvironment to promote growth and survival. It investigates immune checkpoint pathways (e.g., PD-1/PD-L1) that inhibit anti-tumour immune responses and immunosuppressive mechanisms within the tumour microenvironment. Immunotherapy strategies aim to activate and enhance the body's immune responses against cancer, including checkpoint inhibitors, adoptive cell therapies like CAR-T cells, cytokine therapies, and therapeutic vaccines. These approaches harness the immune system's potential to recognize and eliminate cancer cells, offering new treatment options and improving outcomes for cancer patients.